Report of the Cancer Moonshot Task Force: Executive SummaryThis report presents the Task Force's Implementation Plans for accelerating progress, including actions launched under the Cancer Moonshot this year, as well as longer-term plans for continuing momentum into the future. With these goals in mind, the Task Force launched a series of activities in 2016 and developed plans to serve as a "blueprint" for future Administrations (summarized below). Ultimately, through the creation of new paradigms for generating, sharing, and integrating research and clinical data to enhance patient care, the Cancer Moonshot can accelerate the delivery of effective cancer prevention strategies, diagnostics, and treatments to patients in communities around the world.Cancer Moonshot Task ForceCMTF_a616f9f2-99fc-11e6-992f-6d32b2d70f4f... President Obama established the Cancer Moonshot Task Force charged with leveraging federal investments, targeted incentives, private sector efforts, patient engagement initiatives, and more, to support cancer research and enable progress in prevention, diagnosis, and treatment.Joseph Biden, Jr.Vice President, United States -- In his 2016 State of the Union Address, President Obama called on Vice President Biden to lead a new, national "Cancer Moonshot" to dramatically accelerate efforts to prevent, diagnose, and treat cancer  --  to achieve a decade's worth of progress in 5 years. By leveraging decades of scientific understanding from the study and care of cancer, creating and aggregating immensely powerful datasets, and developing unprecedented science and technological capabilities, we as a Nation are positioned to end cancer as we know it.Charles Bolden, JrMember -- Administrator, National Aeronautics and Space AdministrationSylvia Mathews BurwellMember -- Secretary, Department of Health and Human ServicesRobert Califf, MDMember -- Commissioner, Food and Drug AdministrationAshton Carter, PhDMember -- Secretary, Department of DefenseJane Chu, PhDMember -- Chairman, National Endowment for the ArtsFrancis Collins, MD, PhDMember -- Director, National Institutes of HealthFrance Córdova, PhDMember -- Director, National Science FoundationShaun DonovanMember -- Director, White House Office of Management and BudgetThomas Frieden, MD, MPHMember -- Director, Centers for Disease Control and PreventionMichael Froman, PhD, JDMember -- Ambassador, Trade RepresentativeJohn Holdren, PhDMember -- Director, White House Office of Science and Technology PolicyDouglas Lowy, MDMember -- Acting Director National Cancer Institute, National Institutes of HealthGina McCarthyMember -- Administrator, Environmental Protection AgencyRobert McDonaldMember -- Secretary, Department of Veterans AffairsErnest Moniz, PhDMember -- Secretary, Department of EnergyCecilia MuñozMember -- Director, White House Domestic Policy CouncilPenny Pritzker, JDMember -- Secretary, Department of CommerceAndrew SlavittMember -- Acting Administrator, Centers for Medicare & Medicaid ServicesThomas Vilsack, JDMember -- Secretary, Department of AgricultureJeffrey ZientsMember -- Director, White House National Economic CouncilGovernment AgenciesNever before have so many government agencies come together --  committing their leadership and uniting their focus  --  to tackle the challenges along the spectrum of cancer research and care to improve outcomes for patients.Private SectorPrivate sector collaborations and other efforts spurred by the Vice President's leadership, in addition to his vision for igniting new innovation within the biomedical research enterprise, are outlined in an accompanying executive report.Cancer Moon Shot PanelA Blue Ribbon Panel was also formed, which recommended areas of scientific opportunity to complement the Task Force's activities. These collective efforts are not intended to replace existing cancer programs, initiatives, and policies already underway, but rather are focused on areas in which a coordinated effort can dramatically accelerate the pace of progress in the fight against cancer.Cancer Moonshot Task Force StaffGreg Simon, JDExecutive DirectorrLyric Jorgenson, PhDDeputy Executive DirectoDanielle Carnival, PhDChief of Staff and Senior Policy DirectorJerry Lee, PhDDeputy Director for Cancer Research and TechnologiesLauren Leiman, MBASenior Director for External PartnershipsAnabella Aspiras, BSN, MPADirector for Patient EngagementKara DeFrias, MEdDirector of User ExperienceLynne O'Brien, JDPolicy AnalystKatie CollinsPolicy AnalystKathi Hanna, MS, PhDScience WriterLeon FuerthOrganizational Analyst... the end of cancer as we know it._a616fb96-99fc-11e6-992f-6d32b2d70f4fTo dramatically accelerate efforts to prevent, diagnose, and treat cancer _a616fc90-99fc-11e6-992f-6d32b2d70f4fBreakthroughsCatalyze New Scientific Breakthroughs_a616fe16-99fc-11e6-992f-6d32b2d70f4f1We are witnessing widespread and unprecedented optimism that we are on the verge of pivotal advances in oncology research. Under Strategic Goal 1, the Task Force is advancing the pace of scientific discovery by:Biological MechanismsFoster interdisciplinary approaches for elucidating the biological mechanisms underlying cancer onset and treatment_a616fed4-99fc-11e6-992f-6d32b2d70f4f1.1Research & CareAlign research and care as a seamless and iterative process_a616ff9c-99fc-11e6-992f-6d32b2d70f4f1.2Data & BiospecimensMaximize the collection and research use of longitudinal data and biospecimens_a61700b4-99fc-11e6-992f-6d32b2d70f4f1.3DataUnleash the Power of Data_a6170186-99fc-11e6-992f-6d32b2d70f4f2Today researchers are working with an unprecedented amount of data, in part due to the explosion of genomic information, increasing use of electronic health records, and large datasets of clinical, environmental, and public health information. Under Strategic Goal 2, the Task Force is maximizing access to and usability of these data to enhance, improve, and inform the journey of every cancer patient by:Policies & TechnologiesEnable a seamless data environment for clinical and research data through shared policies and technologies_a617028a-99fc-11e6-992f-6d32b2d70f4f2.1Publication & StorageUnlock scientific advances through open publication and storage platforms and next-generation computer architectures_a6170348-99fc-11e6-992f-6d32b2d70f4f2.2WorkforceDevelop a scientific workforce capable of using the open and connected data environment_a617042e-99fc-11e6-992f-6d32b2d70f4f2.3TherapiesAccelerate Bringing New Therapies to Patients_a6170500-99fc-11e6-992f-6d32b2d70f4f3The process by which lifesaving products are moved into clinics is poised for transformation, especially given the access to new and innovative strategies for moving an idea from "bench to bedside." Under Strategic Goal 3, the Task Force is accelerating this transformation by:RegulationFind efficiencies in the regulatory review and licensing processes_a617067c-99fc-11e6-992f-6d32b2d70f4f3.1Collaboration & Data SharingEnhance data sharing across sectors and incentivizing pre-competitive collaborations_a61707a8-99fc-11e6-992f-6d32b2d70f4f3.2Clinical ResearchStrengthen the oncology clinical research enterprise_a6170884-99fc-11e6-992f-6d32b2d70f4f3.3Prevention & DiagnosisStrengthen Prevention and Diagnosis_a6170960-99fc-11e6-992f-6d32b2d70f4f4As we gain an increasing understanding of the causes of cancer, the public can gain cumulative benefits from the broader arsenal of tools for combating this devastating disease. Under Strategic Goal 4, the Task Force is strengthening the Nation's efforts around cancer prevention and diagnosis by:RiskAdvance health programs, policies, and outreach to help Americans reduce their cancer risk_a6170a32-99fc-11e6-992f-6d32b2d70f4f4.1Environmental DeterminantsStrengthen our understanding of environmental determinants of cancer_a6170afa-99fc-11e6-992f-6d32b2d70f4f4.2ScreeningEnhance the cancer screening continuum_a6170bd6-99fc-11e6-992f-6d32b2d70f4f4.3Access & CareImprove Patient Access and Care_a6170ca8-99fc-11e6-992f-6d32b2d70f4f5Cancer PatientsThe Affordable Care Act has provided a unique opportunity for opening the door to health coverage to ensure that patients have access to resources and support throughout their cancer journey. Under Strategic Goal 5, the Task Force is building on this foundation and identifying areas with the greatest potential for meaningful impacts for patients by:Efficiencies & AccessImprove efficiencies of existing programs and expanding current efforts to increase access to health care_a6170d8e-99fc-11e6-992f-6d32b2d70f4f5.1PoliciesTranslate knowledge into workable policies to improve cancer prevention, detection, and quality of care_a6170e56-99fc-11e6-992f-6d32b2d70f4f5.2CareFind new ways of ensuring each and every patient receives quality care during treatment and survivorship_a6170f32-99fc-11e6-992f-6d32b2d70f4f5.32016-10-172016-10-24https://medium.com/cancer-moonshot/report-of-the-cancer-moonshot-task-force-executive-summary-e711f1845ec#.2pw3vcr0bOwenAmburOwen.Ambur@verizon.net