NIH-Wide Strategic Plan FrameworkThis Notice is a Request for Information (RFI) inviting feedback on the framework for the NIH-Wide Strategic Plan for Fiscal Years (FYs) 2021-2025. NOTE: It is important to read this entire RFI notice to ensure an adequate response is prepared and to have a full understanding of how your response will be utilized. Response Date: April 1, 2020The purpose of the NIH-Wide Strategic Plan is to communicate how NIH will advance its mission to support research in pursuit of fundamental knowledge about the nature and behavior of living systems, and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The current NIH-Wide Strategic Plan, covering FYs 2016-2020, was submitted to Congress on December 15, 2015. As part of implementing the 21st Century Cures Act (P.L. 114–255), NIH will update its Strategic Plan every five years. The agency is currently developing an updated NIH-Wide Strategic Plan, for FYs 2021-2025, and anticipates releasing it in December 2020. The FY 2021-2025 NIH-Wide Strategic Plan highlights NIH’s approach towards the achievement of its mission while ensuring good stewardship of taxpayer funds. It is not intended to outline the myriad of important research opportunities for specific diseases or conditions. Nor will it focus on the specific research missions of each component Institute, Center and Office. Those opportunities are found within strategic plans that are specific to an Institute, Center, or Office, or specific to a particular disease or disorder. (A list of Institute, Center, or Office-specific, topical, and other NIH-wide or interagency strategic plans is available at https://report.nih.gov/strategicplans/.) The Framework for the FY 2021-2025 NIH-Wide Strategic Plan, below, articulates NIH’s priorities in three key areas (Objectives): biomedical and behavioral science research; scientific research capacity; and scientific integrity, public accountability, and social responsibility in the conduct of science. These Objectives apply across NIH. In addition, several Cross-Cutting Themes, which span the scope of these Objectives, are identified.National Institutes of HealthNIH_8c9e7852-57cc-11df-8407-a5537a64ea2aHealth is enhanced, life is lengthened, and illness and disability are reduced_f13b8ee0-6995-11ea-b69f-ab8d2c83ea00To communicate how NIH will advance its mission to support research in pursuit of fundamental knowledge about the nature and behavior of living systems, and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability._f13b8f9e-6995-11ea-b69f-ab8d2c83ea00IntegrityAccountabilitySocial ResponsibilityScienceBiomedical & Behavioral SciencesAdvance Biomedical and Behavioral Sciences_f13b9020-6995-11ea-b69f-ab8d2c83ea001Foundational ScienceDrive Foundational Science_f13b908e-6995-11ea-b69f-ab8d2c83ea001.1Disease & HealthPrevent Disease and Promote Health_49ef2892-6a5b-11ea-9f51-705d1a83ea001.2Treatments, Interventions & CuresDevelop Treatments, Interventions, and Cures_49ef2a36-6a5b-11ea-9f51-705d1a83ea001.3Research CapacityDevelop, Maintain, and Renew Scientific Research Capacity_49ef2b44-6a5b-11ea-9f51-705d1a83ea002WorkforceCultivate the Biomedical Research Workforce_49ef2c2a-6a5b-11ea-9f51-705d1a83ea002.1Biomedical Research WorkforceResources & InfrastructureSupport Research Resources and Infrastructure_49ef2cb6-6a5b-11ea-9f51-705d1a83ea002.2Integrity, Accountability & ResponsibilityExemplify and Promote the Highest Level of Scientific Integrity, Public Accountability, and Social Responsibility in the Conduct of Science_49ef2d42-6a5b-11ea-9f51-705d1a83ea003StewardshipFoster a Culture of Good Scientific Stewardship_49ef2dd8-6a5b-11ea-9f51-705d1a83ea003.1PartnershipsLeverage Partnerships_49ef2e64-6a5b-11ea-9f51-705d1a83ea003.2Accountability & ConfidenceEnsure Accountability and Confidence in Biomedical and Behavioral Sciences_49ef2ef0-6a5b-11ea-9f51-705d1a83ea003.3OperationsOptimize Operations_49ef2f86-6a5b-11ea-9f51-705d1a83ea003.4Cross Cutting Themes_49ef301c-6a5b-11ea-9f51-705d1a83ea00DiversityIncrease, Enhance, and Support Diversity_49ef30b2-6a5b-11ea-9f51-705d1a83ea00Women & MinoritiesImprove Women’s Health and Minority Health, and Reduce Health Disparities_49ef3148-6a5b-11ea-9f51-705d1a83ea00WomenMinoritiesData & TechnologyOptimize Data Science and the Development of Technologies and Tools_49ef31de-6a5b-11ea-9f51-705d1a83ea00CollaborationPromote Collaborative Science_49ef3274-6a5b-11ea-9f51-705d1a83ea00Public HealthAddress Public Health Challenges Across the Lifespan_49ef3314-6a5b-11ea-9f51-705d1a83ea002020-02-122020-04-012020-03-19https://grants.nih.gov/grants/guide/notice-files/NOT-OD-20-064.htmlOwenAmburOwen.Ambur@verizon.net